' 
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 3 tablets
Serving Per Container: 83
Amount Per Serving
%DV
Calcium (as calcium carbonate, calcium gluconate, calcium citrate)
1,000 mg
77%
Magnesium (as magnesium oxide, magnesium gluconate, magnesium citrate)
400 mg
95%
Zinc (as zinc gluconate)
15 mg
136%
Sodium†
15 mg
<1%
Top Medical Research Studies
7
Calcium's role in prostate cancer
Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer.
Calcium's isolated impact noted
We investigated how calcium influences prostate cancer cells by creating an experimental setup that mimics the bone microenvironment, which is where bone metastasis commonly occurs. Our approach involved using cell culture vessels coated with amorphous calcium phosphate, a substance designed to simulate the bone matrix. This innovative method represented a significant step forward in modeling the conditions that prostate cancer cells face in the body.
During our experiments, we found that hormone-sensitive prostate epithelial cell lines thrived more effectively on these calcium-rich surfaces. This enhanced adhesion and proliferation suggested that the high-calcium environment somehow supports cancer cell survival, even making them less dependent on androgens.
Furthermore, we observed notable changes in gene expression among early adenocarcinoma cell lines cultured on these amorphous calcium surfaces. These changes appeared to align with biological factors associated with prostate cancer progression, reinforcing the notion that calcium plays a significant role in cancer development and spread.
Overall, our findings emphasize the importance of considering calcium's effects when developing preclinical models for prostate cancer. A deeper understanding of how calcium interacts with cancer cells could provide vital insights into potential treatments and management strategies for affected individuals.
During our experiments, we found that hormone-sensitive prostate epithelial cell lines thrived more effectively on these calcium-rich surfaces. This enhanced adhesion and proliferation suggested that the high-calcium environment somehow supports cancer cell survival, even making them less dependent on androgens.
Furthermore, we observed notable changes in gene expression among early adenocarcinoma cell lines cultured on these amorphous calcium surfaces. These changes appeared to align with biological factors associated with prostate cancer progression, reinforcing the notion that calcium plays a significant role in cancer development and spread.
Overall, our findings emphasize the importance of considering calcium's effects when developing preclinical models for prostate cancer. A deeper understanding of how calcium interacts with cancer cells could provide vital insights into potential treatments and management strategies for affected individuals.
Read More
8
Zinc's complex role in prostate cancer
Prostate cancer-selective anticancer action of an oxindole derivative via HO-1-mediated disruption of metabolic reprogramming.
Limited direct zinc treatment benefits
We explored the relationship between zinc levels and prostate cancer treatments, particularly focusing on a novel compound known as 3D. This compound showed a strong potential to target prostate cancer cells, contributing to a decrease in their proliferation rates.
Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.
We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.
Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.
We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.
Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
Read More
Most Useful Reviews
8.8
Zinc benefits noted
Excellent! It contains zinc, which is beneficial for individuals suffering from prostate cancer.
Read More
8.8
Improved wellbeing
I highly recommend Solgar's Calcium Magnesium Plus Zinc, 250 tablets. Calcium and magnesium promote healthy teeth and normal blood pressure, while zinc is crucial for the prostate and reproductive organs. After a month of taking this supplement, I’ve noticed improvements: my nails are stronger, and I'm more resilient to stress. I take three tablets after dinner as calcium is best consumed at night. Each jar lasts almost three months.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
Zinc's complex role in prostate cancer
Prostate cancer-selective anticancer action of an oxindole derivative via HO-1-mediated disruption of metabolic reprogramming.
Limited direct zinc treatment benefits
We explored the relationship between zinc levels and prostate cancer treatments, particularly focusing on a novel compound known as 3D. This compound showed a strong potential to target prostate cancer cells, contributing to a decrease in their proliferation rates.
Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.
We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.
Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.
We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.
Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
Read More
7
Calcium's role in prostate cancer
Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer.
Calcium's isolated impact noted
We investigated how calcium influences prostate cancer cells by creating an experimental setup that mimics the bone microenvironment, which is where bone metastasis commonly occurs. Our approach involved using cell culture vessels coated with amorphous calcium phosphate, a substance designed to simulate the bone matrix. This innovative method represented a significant step forward in modeling the conditions that prostate cancer cells face in the body.
During our experiments, we found that hormone-sensitive prostate epithelial cell lines thrived more effectively on these calcium-rich surfaces. This enhanced adhesion and proliferation suggested that the high-calcium environment somehow supports cancer cell survival, even making them less dependent on androgens.
Furthermore, we observed notable changes in gene expression among early adenocarcinoma cell lines cultured on these amorphous calcium surfaces. These changes appeared to align with biological factors associated with prostate cancer progression, reinforcing the notion that calcium plays a significant role in cancer development and spread.
Overall, our findings emphasize the importance of considering calcium's effects when developing preclinical models for prostate cancer. A deeper understanding of how calcium interacts with cancer cells could provide vital insights into potential treatments and management strategies for affected individuals.
During our experiments, we found that hormone-sensitive prostate epithelial cell lines thrived more effectively on these calcium-rich surfaces. This enhanced adhesion and proliferation suggested that the high-calcium environment somehow supports cancer cell survival, even making them less dependent on androgens.
Furthermore, we observed notable changes in gene expression among early adenocarcinoma cell lines cultured on these amorphous calcium surfaces. These changes appeared to align with biological factors associated with prostate cancer progression, reinforcing the notion that calcium plays a significant role in cancer development and spread.
Overall, our findings emphasize the importance of considering calcium's effects when developing preclinical models for prostate cancer. A deeper understanding of how calcium interacts with cancer cells could provide vital insights into potential treatments and management strategies for affected individuals.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Zinc benefits noted
Excellent! It contains zinc, which is beneficial for individuals suffering from prostate cancer.
8.8
Improved wellbeing
I highly recommend Solgar's Calcium Magnesium Plus Zinc, 250 tablets. Calcium and magnesium promote healthy teeth and normal blood pressure, while zinc is crucial for the prostate and reproductive organs. After a month of taking this supplement, I’ve noticed improvements: my nails are stronger, and I'm more resilient to stress. I take three tablets after dinner as calcium is best consumed at night. Each jar lasts almost three months.
Read More
